MORE TOWARDS SOLVING A GENETIC MYSTERY IN TYPE-1 DIABETES

	MORE TOWARDS SOLVING A GENETIC MYSTERY IN TYPE-1 DIABETES (© 13 April 2016: Dr.V.M.Palaniappan, Ph.D.)  Large number of medical researchers must have read with great interest the following article that appeared in Medical Xpress (April,11, 2016), and earlier on in Genes and Immunology.  Even before we can discuss my ADDITIONAL, but EARLIER input into this area of research, it would make things easier for non-medical people to understand this very important problem to read the introductory part of what has been published in Medical Xpress: (http://medicalxpress.com/news/2016-04-genetic-mystery-diabetes.html?utm_source=nwletter&utm_medium=email&utm_content=ctgr-item&utm_campaign=daily-nwletter): Solving a genetic mystery in type 1 diabetes According to Stephan Kissler, Ph.D., Investigator in the Section on Immunobiology at Joslin Diabetes Center and Assistant Professor of Medicine at Harvard Medical School (Originally published in: Genes and Immunology): In type 1 diabetes, the immune system attacks the body's own insulin-producing cells. Scientists  don't understand what triggers the attack or how to stop it Now the Kissler lab has shown one way in which one such gene, called RGS1, may help to foster the autoimmune attack. In the attack, immune cells called T cells infiltrate the pancreas and damage the insulin-producing beta cells. Inhibiting RGS1 didn't prevent autoimmune diabetes from happening … in humans … We're continuing to test a number of other genes to see if one strikes us as being a very potent modifier of type 1 diabetes … … this piece of information about RGS1 might become valuable down the line when we know more about other genes… ******** Let me simplify the entire matter, by avoiding the use of too many medical terms, for the benefit of our Blog Readers:  For that matter, even the medical researchers should read this, for the information contained in this throws light on the possibility of a complete cure of the problem.  For a while, let us keep away the intrinsic details concerning the   genes and genetics. Let us talk of what we can understand at ease:  We are very much aware that there are few types in Diabetes:  1.    Type-1 diabetes mellitus, also called Juvenile Diabetes (in the past) or Insulin-Dependent Diabetes mellitus. 2.    Type-2 diabetes mellitus, also called Non-insulin dependent diabetes mellitus. 3.    Diabetes insipidus, characterised by frequent urination. 4.    Pregnancy diabetes, also called Gestational diabetes, and 5.    Drug-induced diabetes.  Certain cells called Beta cells that are present in Pancreas secrete Insulin hormone.  Insulin digests sugar (carbohydrates).  If Insulin production is LESS, all the eaten sugar will not get digested. This results in type-2 diabetes.  To keep the sugar (carbohydrates) digestion in order, insulin supplements are given to the patient, in the form of drugs.  If insulin is given as a supplement from external sources, then there is no need for the Beta cells in the Pancreas even to try to secrete insulin.  (When such a thing occurs in the Thyroid gland, that is, if the thyroxin secretion is NOT enough, then the Thyroid STIMULATING Hormone (TSH) is secreted. THAT induces the gland to secrete MORE thyroxin.)  When it comes to diabetes, there is NO such thing as ‘Insulin STIMULATING hormone’.   However, the sugar WE EAT as part of the food works as Insulin Stimulating Hormone.  In other words, If we eat normal amount of sugar, normal amount of insulin secretes.  If we REDUCE sugar consumption, Insulin secretion also gets reduced.  If we INCREASE sugar uptake, insulin secretion INCREASES proportionately.  This is how the pancreas functions.  *********** Problem would arise if and when abnormal happenings occur.  Like everything else, our body has an optimum / best RANGE when it concerns SUGAR REQUIREMENT.  There is a minimum and maximum for such sugar requirements.  If and when we consume MUCH LESS sugar than the MINIMUM, we become totally energyless, and we can faint, and can even die.  At the other extreme, if and when we consume TOO MUCH sugar than the MAXIMUM our body can tolerate, that too can make us die.  If we consume MUCH LESS sugar, our brain does the following to make us consume MORE sugar, in order to save us from ultimate death.  It makes us feel energyless and exhausted. Our brain gives us a strong desire to eat sugar – a craving occurs. When we eat, the craving stops.  If we OVER-CONSUME TOO MUCH of sugar, our body does the following, in order to save us from ultimate death:  To start with we get the feeling of ENJOYMENT while eating sugar. It is pleasurable.  Once the NEED for sugar is over, we FEEL SATISFIED. So, we want to stop eating more of the sugar.  If we continued eating sugar, then our brain gives us a feeling of HATE. We hate to eat more sugar – we get disgusted, in spite of that food being delicious.  At this stage, let us say some one forces us at gun-point to eat still more sugar.  If and when we eat more, our brain makes us VOMIT, just to save us from the ultimate danger of death.  Our brain, instead of making us vomit, could have simply increased the insulin production to solve the problem at least as a temporary measure.  In reality, the brain does that too, but only as a temporary measure.  However, if we keep on continuing the eating of more and more sugar, and if ALL such sugars are digested with abundant insulin secretion, then the FAR TOO MUCH OF THE DIGESTED SUGAR will kill the cells and us, ultimately - the tissues would rot - similar to the GANGRENE that occurs in the long-term diabetic patients with uncontrolled blood sugar levels all the time, necessitating the amputation of the toes or lower part of the leg.  So, there is a definite need for the brain to totally put a full stop to the eating of too much of sugar.  The brain, since time immemorial, from the time of becoming Homo sapiens from being Apes, or even before that, has associated SWEET TASTE to SUGARS.  In other words, if SUGAR does NOT TASTE sweet, then our brain will NOT induce the secretion of Insulin.  The taste buds in the tongue, the brain, the pancreas, etc. are well inter-connected, inter-dependent, and remain well-coordinated, helped by SALT (Sodium) in its capacity as an essential ELECTROLYTE.  Since a century, Man (not any other animal) has become so intelligent that he has developed capabilities to HIDE the sweet taste from being felt by the taste buds in the tongue*.  (* Similar to adding a likeable perfume to the poisonous mosquito or cockroach killer poison, the original smell of which is extremely bad and repulsive. We would avoid inhaling bad smell, whereas we would  inhale much deeply if perfumed. That results in poisoning our brain and body.)    If for instance, sugar is filled inside CAPSULES, and if the capsules are just gulped, instead of chewing, then our brain will have no knowledge of the entry of THAT sugar into the body.   As a result, brain may not induce insulin secretion, and THIS encapsulated sugar will NOT get digested.   So, the undigested sugar will have to keep floating in the body fluids, doing all possible damages for the well-being of the body*.  (* Swallowing food without chewing will be similar to consuming capsules.  This is one of the major reasons why we must chew our food before swallowing.    In fact, I have recorded that nearly ALL the type-2 diabetic people do NOT chew their food, but gulp them rapidly: see Palaniappan, V.M., 1998. Obesity: Causes, Cure, and Prevention. ISBN 967-9988-0508. 471pp.)  In theory:   If we happen to consume all sugars only in the form of capsules, or if we SWALLOW our food rapidly all the time, as described above, our brain will have no knowledge of the ‘smuggled’ sugar, and thereby loses its management potentials. In other words, our brain gets deceived*.  (* This would happen to Astronauts, if they depend upon encapsulated diet for their survival.)  As a result, FAR TOO MUCH OF SUGAR ends up within the body, and disproportionate insulin quantities leave them to float in the blood in an undigested manner.  This can bring about the death of the cells and the person, as described above.  AT THIS, AN EMERGENCY TO SAVE THE BODY FROM DEATH HAS RISEN!  What can be done?  The best possible measure appears to be a TOTAL STOPPAGE OF THE INSULIN PRODUCTION!  Thus, TWO emergency situations can warrant instantaneous stoppage of insulin production:  1.    When a person consumes awful lot of sugars (recognisable by the taste buds in the tongue), almost non-stop, beyond the body’s tolerance limit, thus inducing the secretion of TOO MUCH of insulin -, beyond the true need.  2.    When sugar is pumped into the body in a hidden state, essentially due to gulping the food without chewing*.  (* 'Pumping' glucose into the body, avoiding the buccal and gastro-intestinal channel, for longer durations would equal this.) Irrespective of the mode of sugar entry, if there happens to be too much of sugar within the body, the best way appears to be a TOTAL STOPPAGE of insulin secretion.  If and when THAT happens, the person gets TYPE- 1 DIABETES.   WE SIMPLY CALL THIS LIFE-SAVING HELP RENDERED BY THE BRAIN AN "AUTO-IMMUNE DISEASE".     IF SUCH AN 'AUTO-IMMUNE DISEASE' DOES NOT HAPPEN, WE WOULD DIE!   THAT BEING THE CASE, INSTEAD OF CALLING IT AN AUTO-IMMUNE DISEASE, WE SHOULD CALL IT "ALTERNATIVE LIFE SAVING MEASURE", RATHER THAN CALLING IT A DISEASE. ******   In Type-I diabetes, if the Beta cells in the Pancreas are NOT dead yet (if it is an early stage), then a REVERSAL should be possible.  In Type II, where the Beta cells are alive but it is only question of LESSER insulin secretion, then a REVERSAL appears to be almost DEFINITELY POSSIBLE.  *********** What I have explained above is all that happens at MACRO-level.  However, if you want to go academic, and if we are to trace the detailed changes at ‘micro-‘ or even at ‘ultra-micro level’ (similar to seeing detailed cellular structures through an electron microscope), then of course, we have to recognise the sequences related to the genes and their interplay.  It would be even more interesting to see the sequence at ‘Nano’ levels.  Irrespective of the approach, the result will be the same.  At macro-level, it would be simple to understand and practise, but will be unimpressive, and may appear as ‘unscientific’.   The other academic approach will be extremely impressive, and much complicated to understand, but will form a necessity for academic excellence. The Ph.D candidates will have to be trained this way to think and interpret information much intricately.  Unfortunately, we do not seem to have much time to wait any further, particularly because the sufferings and the rate of death due to diabetes alone (besides the health-care expenditures), appear to be crossing over the bearable limits of nearly all the nations around the world.  ******** We need to address this issue somewhat ungently.   It should not matter who does the job. Egoism, professional protectionism, so-called medical ethics, etc. should be kept aloof.  It should not matter which discipline of medicine helps to achieve success. All we need is a successful stoppage of the problem, if possible, all at once.  In the first place, WHY IS IT THAT ALL THE RESEARCH FINDINGS DONE HITHERTO WORLD-WIDE DO NOT SEEM TO HAVE THE POTENTIALS TO ERADICATE THE DISEASE?  It should be because, the APPROACH TO SOLVING THE PROBLEM may not be correct.  If the CORRECT PROCEDURE is written in a gold plate and is buried in the South Pole, all the researchers appear to have been digging the soil in the North Pole. This way, they can never find even after a century - the result can be chaotic and disastrous.   In spite of being a non-medical research scientist, I have found the correct procedure for a total prevention and complete cure of the problem – Type-2 Diabetes, in particular.  Of course, my procedure is bound to be VERY HIGHLY CONTROVERSIAL - essentially because of its deviation from prevailing norm. I can very easily do identical kind research work similar to all other researchers, and come up with identical kind of answers, and say that  one should do exercises, avoid sugar consumption, and reduce obesity. This would then CONFORM to what has already been found by a million scientists around the world. Yet, it would never yield any beneficial result, except that I will not be criticised!  Is that my purpose?   I am not expecting a promotion in my workplace, and therefore, I do not need to be scared of criticisms.  I am objective-oriented.   I feel the purpose of my existence is to save mankind at this juncture. God has given me the knowledge. A workable approach will certainly be unique, unusual, abnormal, and will NOT conform to the non-working approaches that are being repeatedly said by others.  ************ Gunther S. Stent from University of California in Berkeley calls my kind of report as “PREMATURE DISCOVERY”. He, along with his colleague Barber, emphasizes in their paper that discoveries that were not consistent with the accepted knowledge at the time or not verifiable technologically would experience the delayed phenomenon. “delayed recognition papers are those that are initially unappreciated or unused but are later recognized as significant”  Dr. Eugene Garfield, Founder of the Institute for Scientific Information (ISI), who was a pioneer in the field of citation analysis, and whose data bases have now become the online research tool of the “Web of Knowledge” (Infoplease, 2007), writes:  “Recognition is one of the most valued rewards of science. It often is confirmed exclusively on the individual or team responsible for a particular breakthrough. “These fortunate few certainly deserve the media attention and awards that come with the success of discovery.” “It is almost impossible to identify useful, important, yet unrecognized papers by any but highly subjective evaluation, but we can recognize a special class of undervalued papers – those that were recognized long after they were published. Such papers represent DELAYED RECOGNITION and sometimes are associated with PREMATURE DISCOVERY.”  “… PREMATURE DISCOVERY IS A SUBJECT OF DELAYED RECOGNITION. “A definition, according to Stent, is that the discovery “was not appreciated in its day. “This can occur when the contemporaneous knowledge, technology, and social issues prevent the discovery from being extended experimentally or applied to other related scientific efforts.”  Garfield adds on: According to William Goffman in Cleveland’s Case Western Reserve University and Kenneth S. Warren of the Rockefeller Foundation in New York, “…A strong presumption prevails that any evidence that contradicts the accepted view is invalid and must be disregarded…” It seems, Barber had well defined in 1961 itself about the topic of resistance by scientists to new discoveries (especially those that challenge commonly held percepts). Likewise, if one does not follow the well-ploughed path of presentation of his/her discoveries, the chances of those findings getting totally ignored appear to be great. The fact that a particular research is done in a deviated manner from the so-called ‘norm’, should, by right, be considered to show the extra capabilities and exceptional talent of the researcher. Again, Eugene Garfield’s (1989) another thought-provoking article entitled “The Process of Scientific Discovery” has brought to recognition my kind of approach.   If all of MY discoveries published in 1998 (and subsequent years) in the form of a books with proper ISBN reference and the like) is considered to constitute 100%, recent scientists from different parts of the world have been publishing these days bits and pieces of my findings (amounting to 5 or 6 percent of my works) as if theirs is the first-time report (may not form plagiarisms), simply because they have not seen my publications – for want of adequate citations and publicity, especially because I do not belong to the mainstream medical fraternity. Thus, my findings tend, erroneously, to form one of the multiple discoveries. I have been trying for the past 41 years, through multivariate means, to get my findings recognized. None of them brought me any success.  Could you, if you have any authority,  kindly evaluate my works, and do the needful to bring them to recognition soon, so that the suffering millions worldwide can be saved from nearly all of the diseases, thus making their life on earth more pleasant, contributive and meaningful.  ********** THE WORLD HEALTH ORGANISATION, or any Health Ministry in any of the countries, must come forward to recognise my findings.    FOR THAT MATTER, EVEN OUR MALAYSIAN HEALTH MINISTER  Dato Sri Dr. S. Subramaniam, and/or his Deputy Dato Seri Dr.Hilmi Yahaya, who support any alternative medicine if it can help the people rid of their health problems, could invite me to implement my findings in one of our well-established and most modern hospitals in Kuala Lumpur / Selangor (Such as the Selayang Hospital),  I will do the needful, demonstrate excellent and highly disciplined scientific procedure and show positive results within a short time span of even TWO MONTHS, incurring insignificant expenditure. ******** Well friends, I look forward to some magical changes to occur this year. With best wishes, Dr. Palani, Ph.D.

 

WEIGHT CAN NEVER BE LOST THROUGH EXERCISES FOR THE PREVENTION OF OBESITY-RELATED DISEASES

WEIGHT CAN NEVER BE LOST THROUGH EXERCISES FOR THE PREVENTION OF OBESITY-RELATED DISEASES.

(© 30 January 2016: Dr. V.M. Palaniappan, Ph.D.)

I am able to exclaim with such a great definiteness that MORBID OBESITY can never be lost through exercises.

If I may add to the above another identical statement with equal definiteness, it will be that MORBID OBESITY CANNOT BE REVERSED THROUGH FOOD REDUCTIONS as well.

This is so because, they have absolutely NOTHING TO DO WITH FAT ACCUMULATION, as has been totally misunderstood by all the researchers involved in this area of health science.

May I emphatically put it, based on my 41 years of study in this area, that ALL the DISEASES linked to OBESITY are the result of certainly NOT fats and/or oils (or EXCESSIVE CALORIES), but of the ACCUMULATION of far too much of CALCIUM inside the CELLS.  

If the obesity or body weight has anything to do with just food/calories, then, the strenuous exercises, or even STARVATION should be able to reverse the process*.

 (* You can often see some obese people starving, but yet, they would not lose any bit of their weight. Instead, many of them would complain that their body weight has been increasing non-stop.

Of course, scientists would then label such situations as ‘adament’ fat, and the like**.)

(** In Malaysia, recently, in the POLICE force, they declared that promotion will not be given to those obese officers if they fail to reduce their obesity. Most of the people are said to have been sincerely (a) cutting down on their food, and (b) doing strenuous exercises. Nevertheless, numerous people appear to have failed to achieve any success. It seems, consultations with medical doctors too did not help them to any extent.

Now, after reading this, people, including those Police Officers, should know why they couldn’t succeed in their sincere attempts.

If I am consulted by either the Police HQ, or the Ministry of Health, I would gladly guide them to succeed through a very simple DECALCIFICATION PROGRAMME.

Our present Minister for Health appears to be going all out to restore the health of all Malaysians, and also those foreign nationals working here on permits. As it is, he seems to be fully concentrating on weeding out the serious viral epidemics.

Anyway, I hope he would soon invite me for a possible implementation of my programme for the benefit of all the people here.)

*   *   *   *   *   *

Of late, a new explanation that appears to be another attempt in this series is the news that has appeared in Medical Xpress (28 Januray 2016), http://medicalxpress.com/news/2016-01-wont-weight.html?utm_source=nwletter&utm_medium=email&utm_content=ctgr-item&utm_campaign=daily-nwletter with the following heading:

“Why you won't lose weight with exercise alone”

“Our bodies adapt to higher activity levels, so that people don't necessarily burn extra calories even if they exercise more.”  (Herman Pontzer, University of New York, in Cell Press journal Current Biology, 28 Jan. dx.doi.org/10.1016/j.cub.2015.12. 046)

 Dr. Pontzer and his fellow workers have also found that “The most physically active people expended the same amount of calories each day as people who were only moderately active," and that has relevance to the above theory he has put up.  

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TALKING OF MORBID OBESITY:

I strongly believe none of the above explanations would fit into the reality.

Please think of the SHEEP/LAMB in cold countries or mountains, and compare them with the GOATS that live in the lowlands of tropical countries.

The sheep has a definite need to protect itself from the freezing cold, more so in winters. The only thermal protection they have is to develop a THICK layer of FAT – the lard!

So, even those herbivorous animals that are 100% vegetarians, synthesize FATS, form very thick layer under their skin, and withstand the intense cold.

Whereas, the tropical-living goats do not develop such a thick layer of fat, even if they OVER-EAT (graze) abundant GRASSES (or vegetable matter), similar to the elephants.

In other words, eating EXCESSIVE FOOD – a lot more than what is needed for its survival, whether the food be are of animal origin or of plant matter (OR, accumulating unlimited quantities of CALORIES), will NOT make an animal MORBIDLY OBESE, with thick FAT LAYERS under their skin of TROPICAL animals.

Likewise, EVEN INADEQUATE food consumption would, out of necessity, would enhance the production of FAT CELLS/lard (adipose tissues) in the animals that are genetically-designed (during the process of evolution) to live in the COLD countries.

Thus, excessive food/calories will NOT give rise to THICK FAT LAYER in tropical goats, and reduced food consumption will NOT prevent the formation of such thick fat layers in SHEEP.

It should be clear from the above observation that MORBID OBESITY in ALL the people, irrespective of the CLIMATE or ENVIRONMENTAL TEMPERATURE, will NOT occur due to OVER-EATING or accumulation of EXCESSIVE CALORIES.

The humans in cold countries do NOT live directly in the midst of ice, as does the mountain sheep. Even if they happen to live in the Polar Regions, they CREATE WARMTH and live in its midst. So, humans should not be compared with animals that live in the open in cold regions*.

(* Sheep can live in the open areas in the high mountains, whereas man will die there, without protection.

However, he would eat MORE food to derive more calories so as to him warmer there.

If he happens to eat ABUNDANT food – more than what is required, such food energy will get stored, perhaps only a little in the form of adipose tissue. However, that extra food as such may not give him the diseases, such as kidney stones, diabetes, heart blockages, blood vessel thickenings (atherosclerosis), etc**.)

(* All these diseases need something else than the mere adipose tissues.)

The truth is, irrespective of the climate or geographical location (latitude or longitude), it is simply THE ACCUMULATION OF CALCIUM WITHIN THE CELLS that INCREASES the body WEIGHT of a person.

Such calcium accumulations, when they EXCEED the body’s TOLERANCE limit – the threshold point, give rise to the DISEASES – the morbid obesity!

The above being the case, if a person is going to starve, or does even non-stop strenuous exercises and burn totally all the calories to zero balance, of what use can that be for the removal of calcium from the cells?

The calcium will not get reduced any bit. Instead, the exercises would only INCREASE the build-up of MORE calcium* within the cells, and that would then increase the total body weight.

(* due to loss of water through dehydration, and thereby giving rise to under-urination.)

However, when an obese person does strenuous exercises, he does lose some of his body weight – to statistically significant extent.

Now, how does this happen?

The LITTLE adipose tissues that have become the STORED food energy get lost, and that would naturally give SOME amount of positive result. That will be all to it.

We can consider another situation:

When a person eats MUCH LESS food all the time, he does NOT become obese.

In this case, of course, even the little adipose tissue would not form. However, the little food would only contribute little calcium. So, THAT little calcium will not be able to bloat up the cells (i.e., inflammation will not occur).

If a person consumes TOO MUCH of food, that BULK would naturally contribute TOO MUCH of calcium, which will make him truly obese, with diseases.

Yet, some people who consume too much of calcium do not seem to become obese. How can this be explained?

This takes us back to the original explanation I have been offering all the time.

ALL UNWANTED EXCESSES (in this case, the calcium excesses) will get REMOVED from the body through URINATION.

The problem of EXCESSIVE CALCIUM ACCUMULATION and RELATED MORBID OBESITY would occur only if the person UNDER-URINATES all the time.

Reduced urination can remove only a reduced quantity of the calcium excesses.

Most of the calcium excesses would stay back within the body of the under-urinating person*.

(* This has relevance to the saturation point of salt)

As said earlier, these calcium excesses enter into the cells and get stored.

Naturally, such storages would increase the body weight, and this weight has nothing to do with adipose tissues, nor expendable food energy.

Calcium is a plain mineral that normally goes into the makeup of some of the body structures, such as bones, teeth, nails, and numerous other components, but would not provide energy for work.

The basic requirement of a person happens to be about 450 or 500 mg of calcium, on a daily basis.

While this being the case, if the person consumes, say 50,000 mg of Calcium, and does not have any food-derived energy in him, THIS calcium excess would not provide him any bit of energy.

How do these calcium excesses accumulate within the body of a person who does not take mega doses of calcium supplements?

Let us see the process:

*   *   *   *   *   *  

In the process of defining certain phenomenon, I will be repeating a few statements, and I hope you will not get ‘fed up’ with my behaviour.

Such a repetition becomes imperative essentially because, I cannot change or alter the TRUTH, simply for the sake of avoiding repetitions.

Some of the substances that enter into our body through air, water, and food can dissolve in water, and a few others will not dissolve in water.

Salt, sugar, calcium, etc. are water-soluble.

If we happen to consume excessive salt or calcium, those excesses will get out of our body before harming us.

When it comes to sugar, for instance, if we consume excesses of it, under normal circumstances, it will not get out of the body as part of the urine. Instead of it, it will get converted into stored energy in the form of adipose tissues – similar to a battery.

*   *   *   *   *   *

When it comes to EXCESSIVE SALT consumption, the story appears to be different:

I am sure you can recollect the meaning of the word  “Catalyst”, if I mentioned it here.

A catalyst is also a ​substance that ​causesor ​speeds a ​chemical ​reaction without itself being ​changed.  http://dictionary.cambridge.org/us/dictionary/english/catalyst)

SALT should be considered as a CATALYST.

It will speed up the functions of the brain and central nervous system, besides several other activities, without itself getting lost or used up in that process.

Once its work is over, it gets out of the body as part of the urine, and does NOT cause any harm to the body at all!

However, if the person UNDER-URINATES, then those used-up salt + the new salt intake though regular food consumptions, end up becoming TOO MUCH in quantity, reaching undesirable levels.

Only then, the blood become thickened, resulting in RAISING its PRESSURE, but not otherwise*.

(* So, this would explain that salt is NOT a culprit for blood and heart diseases. It is UNDER-URINATION, perhaps also related to REDUCED water consumption, OR loss of body water through sweat-out exercises, dehydration by air-conditioners, and the like.)

*   *   *   *   *   *

How about CALCIUM?

It is similar to a BRICK in the building construction.

If men require about 450 mg of bricks daily to build up the day-to-day utilities, women’s need will be about 500 of them.

When MORE bricks are delivered, what do you think would happen to such excesses?

Under normal circumstances, the EXTRA bricks are returned to the supplier – sent out of the body in the urine.

If and when a person UNDER-URINATES, then, these calcium excesses, for want of choice, get STORED within the body.

The only available store house appears to be the CELLS.

All SOFT cells in any part of the body has the potentials to store these calcium excesses.

Likewise, all the BONE cells too have identical capacities.

The choice appears to depend upon the availability or unavailability of vitamin-D.

If the body of that person has enough of vitamin-D (either through exposure to sunshine, or through supplementation), those calcium excesses would end up getting impregnated to become part of the skeletal system.

In the absence of vitamin-D, those calcium excesses will enter into the soft cells, and stay there.

The problem would become immense only when such calcium accumulations reach a stage that cannot be tolerated any more.

The soft cells, for instance, would split continuously (mitotic cell divisions) to accommodate the continuously coming up calcium excesses. This would then make that location – the tissues, to bloat up, resulting in INFLAMMATION.

A while later, along with progressive additions, these swollen structures would become lumps, tumours and cancers.

If the calcium excesses enter into the LYMPH DUCTS, accumulate and dry up there, then cancer of the lymph ducts develop.

Entry of the calcium excesses into the bone marrow can give rise to any of the leukaemia cancers.

*   *   *   *   *   *

The prevention of disease-causing overweight, obesity, stone diseases, type-2 diabetes, hypothyroidism, heart blockages, tumours and cancers can be achieved by an extremely simple method – all that is required is LIBERAL URINATION.

Through my 41 years of study, I have found that a person will have to drink about 2 – 3 L of plain water (not juices, and the like), and URINATE nearly ALL OF IT.

Such an Input/Output, if monitored correctly, should give a ratio of 1.0.

A ratio not exceeding 1.2 appears to be safe to keep a person in a healthy state.

Anything beyond that, 1.5 or 2.0, for instance, would indicate that the person has already developed HYPERHIDROSIS (sweating profusely in palms, feet, and all over the body), and is also in the process of becoming overweight and morbidly obese.

*   *   *   *   *   *

By practising the above, I have cured a large number of patients who came to me with such non-communicable diseases, during the past 41 years.

WILL THE WORLD HEALTH ORGANISATION (W.H.O) GIVE ME AN OPPORTUNITY TO PROVE TO THEM WHAT I HAVE STATED ABOVE IN THIS ARTICLE, SO THAT THE ENTIRE WORLD WOULD GET BENEFITED IMMENSELY?

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Dear Friends,

Thanks for reading this long article.

If you have the means of communicating with the Authorities of W.H.O., kindly do so, and God will bless you for that!

OK, bye,

Dr. Palani, Ph.D.