A NEW DIABETIC DRUG MAY CAUSE BLADDER AND BREAST CANCERS

A NEW DIABETIC DRUG MAY CAUSE

BLADDER AND BREAST CANCERS

If you click the following link, it would take you to Medical News Today (15 July 2011):http://www.medicalnewstoday.com/articles/231187.php 

I saw there the following news written by Christian Nordqvist:

(This discussion is going to be somewhat hard-going, and and may not interest many of you, unless you are a Serious Reader. Please do not blame me if it is going to be 'boring' to you...you can skip this, if you wish.. Dr. Palani)

Diabetes Drug Dapagliflozin May Cause Bladder And Breast Cancers, Says FDA


A new diabetes pill dapagliflozin is effective but may cause bladder and breast cancer, says the FDA as it decides whether to approve the medication.

According to the FDA dapagliflozin does not work so well in diabetes patients with impaired kidney function. The reviewers also mentioned liver injury, bone safety, and urinary and genital infections.

Some market experts predict that the FDA may ask for more evidence of dapagliflozin's effectiveness before deciding on whether to approve it.

THE FOLLOWING ARE MY VIEWPOINTS & A HUMBLE SUGGESTION TO THE RESEARCHERS CONCERNED:

I have found out that UNDER-URINATION (e.g., just twice or thrice a day, daily), as a MAJOR risk factor, appears to be giving rise to (otherwise healthy individuals who may not take any form of drug) bladder, breast and a several more cancers.

My interpretation, as I have presented in most of my books, is:


Excess free calcium within the body gets removed from the body through approximately 8 urinations, to the extent of making the Input/Ouput Ratio to remain at 1.0, for most of the time. That leaves the body in good health.

If and when a person under-urinates (e.g., just twice or thrice daily), the calcium excesses tend to stay within the body.


Over a period of time, repeated retentions of such excessive calcium results in an excessive accumulation, reaching a level that is beyond the tolerance limit (threshold point) of the body.

Such free calcium enters into soft cells, such as the breast and kidneys, making them hypertrophic at initial stages, and hyperplasia on crossing over the threshold levels. It then appears to result in cancer.

(There are scientific papers that indicate the rapid absorption of glucose by the cells that make up the cancer. This may enlarge the cancer structure. However, this is not the point I am interested in indicating here.)


My suspicion, with reference to the possible development of cancers doubted to be related to the new diabetic drug right now is:


IF THE NEW DRUG DECREASED THE FREE FLOW OF URINE, AND ENHANCE ITS RETENTION WITHIN THE BODY, THERE IS EVERY ROOM FOR THE DEVELOPMENT OF CANCERS.


THE ABOVE IS MORE PROBABLE BECAUSE, THE URINE THAT GETS STAGNATED IN THE URINAL BLADDER CAN MAKE AVAILABLE ITS CALCIUM CONTENT TO BE ABSORBED BY THE CELLS THAT MAKE UP THE INTERNAL WALL OF THE BLADDER (BY THE EPITHELIAL CELLS, THUS GIVING RISE TO CARCINOMAS, AND NOT SARCOMAS), AND GIVE RISE TO BLADDER CANCER.


MY INTERPRETATION APPEARS TO GET STRENGTHENED BY THE FOLLOWING STATEMENT MADE BY THE FDA: “…does not work so well in diabetes patients with impaired kidney function…”.


WHEN IT COMES TO THE BREAST, THE LACTICIFEROUS (milk ducts) TISSUES THERE THAT ARE DESIGNED TO SCAVENGE CALCIUM FROM ALL SOURCES (IN ORDER TO PRODUCE / SECRETE MILK) TEND TO ABSORB THE FREE CALCIUM THAT GETS RETAINED WITHIN THE BODY DUE TO UNDER-URINATION PROBABLY CAUSED BY THE NEW DIABETIC DRUG.

My above interpretations appear to make sense. More information pertaining to the phenomenon of the said two cancers can be read in Page 443, in my book "CANCER: CAUSES, CURE and PREVENTION” (ISBN 978-967-9988-14-7. 2010. 624pp).

If my interpretation can be accepted, it may become worthwhile for the Manufacturers of the said drug to find by research a method to overcome the new drug’s undesirable suppressive effect over urine production.

To pursue the research along these lines, the water (liquid) intake and urine output may have to be monitored in all those people subjected to the study.

The researchers, I think, could also contemplate about the possibility of recommending this drug for use by:

(a) only those who do not have urinary problems, including ‘impaired kidney function’,

(b) modify the chemical composition of the drug so as to eliminate only the urinary suppressive effect, if that happens to exist in it, and

(c) undertake trials using this drug in combination with some diuretics so as to regulate the urine output to about 8 times per day - and not more to the extent of creating drug-induced Diabetes Insipidus, nor less that could give rise to the already ‘doubted-to-exist’ under-urination.

My recent book “Diabetes: Causes, Cure and Prevention” (ISBN978-967-9988-15-4; 256pp) should prove useful to all those interested in understanding all the above.

Such a modification may help in making the drug usable for the benefit of diabetic patients.

While suggesting all the above, I do realise my limited knowledge in biochemistry, pharmaceutical formulations, medicine, and the like.

Again, basically being an Ecologically-oriented Complementary Medical Practitioner and Researcher, I am not in favour of promoting the use of synthetic drugs, wherever natural methods are available for a possible cure of any of the diseases humans may suffer.

My primary objective in making the above observation is to RE-EMPHASISE MY FINDINGS in the area of Ecological Healing System, wherein I have found under-urination as one of most important causes / risk factors for the development of cancers in breast, bladder, and the like, as I have explained in my book ‘Cancer: Causes, Cure and Prevention”.

Apart from this, I do not intend to interfere with the proceedings that have been going on in the concerned sectors, including the FDA.

Ok, friends, with best wishes to all,

Talk to you later…

Dr. Palani